Survodutide Powder CAS 2805997-46-8

Survodutide Powder CAS 2805997-46-8
Details:
Product Name: Survodutide Powder
CAS Number: 2805997-46-8
Molecular Type: Synthetic Peptide
Appearance: White to off-white lyophilized powder
Purity (HPLC): ≥ 98% (typical, customizable upon request)
Identification: HPLC, Mass Spectrometry (MS)
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Description
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Product Overview

 

Survodutide Powder (CAS 2805997-46-8) is a high-purity, synthetic peptide compound supplied as a lyophilized white to off-white powder. It is designed for scientific research, analytical studies, and pharmaceutical development workflows, including peptide characterization, formulation research, and reference standard use.


As a next-generation dual-pathway peptide structure, Survodutide Powder has attracted growing interest from biotechnology companies, pharmaceutical R&D teams, and contract research organizations (CROs) worldwide. Its well-defined amino acid sequence, reproducible synthesis process, and strong batch-to-batch consistency make it suitable for demanding research environments that require reliable peptide materials.

 

Molecular Mechanism & Clinical Rationale

 

The therapeutic power of Survodutide lies in its sophisticated dual-agonist design:
GLP-1 Receptor Activation: This pathway is well-established for promoting insulin secretion in a glucose-dependent manner, delaying gastric emptying, and enhancing satiety in the brain, leading to reduced caloric intake.

 

Glucagon (GCG) Receptor Activation: This is the differentiating factor. Glucagon receptor agonism increases energy expenditure by enhancing hepatic fat metabolism and thermogenesis. This creates a synergistic effect: while GLP-1 activity reduces energy input, glucagon activity increases energy output.

 

This dual action is supported by compelling clinical evidence. A Phase II trial demonstrated that after 46 weeks of treatment, subjects on the highest dose achieved body weight reductions of up to 19%. Notably, 40% of participants in the high-dose group achieved a weight loss of ≥20%, and the weight loss curve had not plateaued by the end of the study period, suggesting potential for even greater efficacy with extended treatment.

 

Product Specifications & Quality Assurance

 

Our Survodutide Powder is synthesized and controlled under stringent quality standards to ensure consistency and reliability for your critical research applications.

 

Key Research & Development Applications

 

Survodutide is a versatile tool for exploring new frontiers in metabolic disease:

Obesity Pharmacology: Investigate the superior efficacy profile of dual agonism compared to single GLP-1 agents in models of diet-induced obesity.

MASH/NASH Therapeutics: Explore its significant potential as a best-in-class treatment. A Phase II study showed 83% of adult MASH patients achieved statistically significant histological improvement with Survodutide, compared to placebo.

Mechanistic & Combination Studies: Unravel the precise contributions of GCG vs. GLP-1 receptor activation to overall metabolic benefits, or study potential synergies with other therapeutic agents.

Formulation Development: Support early-stage work on novel delivery systems (e.g., sustained-release formulations) for this promising peptide.

 

Sourcing & Partnership

 

We specialize in providing high-grade Survodutide Powder (CAS 2805997-46-8) to support the global research community. Our product is offered in various packaging sizes, from milligram quantities for initial assay development to gram-scale for extended preclinical studies.


Intended Use Statement:
This product is supplied as a biochemical research tool. It is intended for laboratory research use only by qualified professionals. It is not for diagnostic or therapeutic use in humans or animals.

 

Packaging & Supply Capabilities

 

To meet the diverse needs of global buyers, Survodutide Powder is available in flexible packaging options, including:
Small-scale research quantities
Pilot-scale development batches
Bulk supply for long-term projects
Packaging is designed to protect product integrity during international shipping and long-distance transport.
Custom labeling, documentation formats, and packaging configurations are available for professional buyers.

 

Documentation & Regulatory Support

 

Each shipment of Survodutide Powder (CAS 2805997-46-8) can be accompanied by:
Certificate of Analysis (COA)
HPLC chromatograms
Mass spectrometry data
Batch traceability records
Safety and handling documentation (upon request)
This documentation supports internal quality review, supplier audits, and project compliance requirements.

 

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