China Intermediate Manufacturers Suppliers Factory - Customized Intermediate Wholesale

Your Professional Intermediate Supplier

TNJONE is a professional manufacturer of pharmaceutical raw materials, APIs, peptides, and intermediates with over 10 years of industry experience. We operate a GMP-compliant factory in Shaanxi, China, serving pharmaceutical, research, and healthcare applications.

Strict Quality Control

Professional QA and QC teams ensure stable purity, reliable performance, and full production traceability.

Custom Manufacturing

Advanced production and testing equipment support flexible OEM/ODM solutions for different product requirements.

Reliable Supply & Delivery

Efficient production management and professional logistics help ensure stable supply and safe global transportation.

4-Biphenylylmethyl Acrylate Powder CAS 54140-58-8
5-Product Name: 4-Biphenylylmethyl Acrylate Powder CAS Number: 54140-58-8 Molecular Weight: Approx. 238.28 g/mol Appearance: White to off-white crystalline powder Purity (HPLC): ≥ 98.0% (customizable)
4-phenylbenzaldehyde Powder CAS 3218-36-8
Product Name：4-Phenylbenzaldehyde Powder Chemical Name：4-Phenylbenzaldehyde CAS Number：3218-36-8 Molecular Formula：C₁₃H₁₀O Molecular Weight：182.22 g/mol Appearance：White to off-white crystalline
5,5'-oxybis(isobenzofuran-1,3-dione) Powder CAS 1823-59-2
Product Name: ODPA PowderCAS Number: 1823-59-2 Molecular Formula: C16H6O7 Molecular Weight: 310.21 g/mol Appearance: White to off-white crystalline powder Purity (HPLC): ≥ 99.0%
2,2-Bis(3-(3-aminobenzoylamino)-4-hydroxyphenyl)hexafluoropropane (6FDAP / HFHA) Powder...
Product Name: 2,2-Bis(3-amino-4-hydroxyphenyl)hexafluoropropane Synonyms 6FDAP; HFHA PowderCAS Number: 220426-92-6 Molecular Formula: C₁₅H₁₀F₆N₂O₂ Appearance: Off-white to light yellow crystalline
4,4'-(Hexafluoroisopropylidene)diphthalic Anhydride Powder CAS 1107-00-2
CAS: 1107-00-2Appearance: White crystalline powder or fine granules.Specification: ≥99.0% (by GC or HPLC)Molecular Formula: C₁₇H₆F₆O₆Molecular Weight: 444.22 g/molShelf Life: 24 months(Proper
Fmoc-L-Lys[C20-OtBu-Glu(OtBu)-AEEA-AEEA]-OH Powder CAS 2915356-76-0
CAS: 2915356-76-0Appearance: Light brown to off-white fine powderMolecular Formula: C66H105N5O16Molecular Weight: 1224.57 g/molShelf Life: 12-24 monthsStock: No stock, exclusively
C(RGDfK(N3)) Powder CAS 868845-09-4
CAS: 868845-09-4Appearance: White to off-white lyophilized powderMolecular Formula : C27H39N11O7Molecular Weight: 629.68Shelf Life: 24 months(Proper Storage)Stock: Adequate StockCertificate: lSO,
Di-tert-butyl Dicarbonate Powder CAS 1007089-84-0
Product Name: Di-tert-butyl dicarbonate (Boc₂O) CAS Number: 24424-99-5 Molecular Formula: C₁₀H₁₈O₅ Molecular Weight: 218.25 g/molAppearance: White to off-white crystalline powderAssay (Purity): ≥
3-(Chloromethyl)-5-methylpyridine Powder CAS 57960-84-6
4-Product Name: 3-(Chloromethyl)-5-methylpyridine Powder CAS Number: 1007089-84-0 Molecular Formula: C₇H₈ClNMolecular Weight: ~141.60 g/mol Appearance: White to off-white crystalline powder Purity: ≥
Ethyl 2-(4-aminophenyl)butanoate Powder CAS 57960-84-6
Appearance: White to off-white crystalline powderCAS NO: 57960-84-6Molecular Formula: C12H17NO2Molecular Weight: 207.27Purity: ≥98.0% (HPLC)Melting Point Range: 68–72℃Loss on Drying: ≤0.5%Packaging:
2-(4-nitrophenyl)butanoic Acid Powder CAS 7463-53-8
Chemical Name: 2-(4-Nitrophenyl)butanoic Acid (4-Nitrophenylbutyric Acid)CAS Number: 7463-53-8Molecular Formula: C10H11NO4Molecular Weight: 209.20 g/molPurity: ≥98.0% (HPLC Grade)Physical Form: Light

We offer an extensive portfolio of high‑purity chemicals that serve as essential synthetic building blocks for both industrial applications and scientific research.

Specification

CAS Number	57960-84-6
Molecular Formula	C12H17NO2
Molecular Weight	207.28
IUPAC Name	Ethyl 2-(4-aminophenyl)butanoate
Synonyms	Indobufen Impurity 26; 2-(4-aminophenyl)butanoic acid ethyl ester
Appearance	White crystalline powder
Melting Point	60.3°C
Boiling Point (760 mmHg)	334.8°C
Density (25°C)	1.060 g/cm³
Solubility (25°C)	≥5 g/L in water; freely soluble in ethanol, methanol, dichloromethane
Refractive Index (n20/D)	1.534

Types of Intermediate

The Intermediate produced by our company mainly include the following types:

Pharmaceutical Intermediate

Pharmaceutical intermediate is a chemical compound produced during the multi-step synthesis of an Active Pharmaceutical Ingredient (API). It serves as a molecular building block that undergoes further chemical reactions or purification to eventually become the active drug.

Chemical Intermediate

In chemistry, an intermediate is a short-lived, transient molecule formed during a multi-step reaction. It is produced in one step and consumed in a later step. Because it is entirely used up before the reaction finishes, it does not appear in the overall balanced chemical equation.

4-phenylbenzaldehyde Powder CAS 3218-36-8

Advantages of Intermediate

Building Blocks for APIs

Active pharmaceutical ingredients (APIs) are the core components responsible for the therapeutic effects of drugs. However, APIs cannot be produced directly. Instead, they are synthesized through a series of chemical reactions that require specific intermediates to build the molecular framework of the final drug.

Customizable Synthesis Routes

The pharmaceutical industry often requires tailored synthesis routes to create specific molecular structures for new medications. Chemical intermediates provide flexibility in the synthesis process, allowing pharmaceutical manufacturers to fine-tune reactions and optimize pathways to produce high-purity APIs.

Ensuring Drug Purity and Efficacy

The quality of chemical intermediates has a direct impact on the purity and efficacy of the final pharmaceutical product. Impurities in intermediates can lead to unwanted side effects, reduced potency, or even drug recalls, which can be costly and damaging to a company’s reputation.

Cost-Effective Production

In addition to their importance in drug efficacy and safety, chemical intermediates also play a significant role in controlling manufacturing costs. Pharmaceutical production is expensive due to the complexity of chemical reactions, the need for high-purity materials, and compliance with stringent regulatory standards.

Applications of Intermediate

Antibiotics

Many antibiotics, including penicillins and cephalosporins, are produced using specific chemical intermediates that are crucial for constructing the beta-lactam ring, the core structure of these drugs.

Anticancer Drugs

Chemotherapy medications require the careful assembly of complex molecular structures. Intermediates allow for the precision needed to synthesize cytotoxic agents that target cancer cells effectively.

2,2-Bis(3-(3-aminobenzoylamino)-4-hydroxyphenyl)hexafluoropropane (6FDAP / HFHA) Powder CAS 220426-92-6

Fmoc-L-Lys[C20-OtBu-Glu(OtBu)-AEEA-AEEA]-OH Powder CAS 2915356-76-0

Cardiovascular Drugs

Drugs that regulate blood pressure, cholesterol, or heart function often rely on intermediates to ensure precise therapeutic properties and to maintain high levels of efficacy.

Antiviral and Antiretroviral Drugs

Intermediates are essential in the synthesis of drugs that target viral infections such as HIV, Hepatitis, or influenza, helping to develop effective treatments for viral diseases.

Di-tert-butyl Dicarbonate Powder CAS 1007089-84-0

Precautions for the Storage of Intermediate

All intermediates must be stored in a safe, secure location.

Shelves should be level, stable, and secured to the wall or another stable

Store intermediates away from direct sunlight, sources of heat, and egress pathways

Hazardous intermediates must be stored below eye level.

Do not store intermediates on the floor, window ledges, or balconies.

Ethyl 2-(4-aminophenyl)butanoate Powder CAS 57960-84-6

3-(Chloromethyl)-5-methylpyridine Powder CAS 57960-84-6

Keep containers closed unless you are dispensing a intermediate or adding to the container.

Provide secondary containment for liquids whenever possible. Dishpans or polyethylene trays work

Don’t store intermediates in a sink or fume hood, except for certain toxic gases that are so dangerous they can only be stored in a gas cabinet or fume

Label containers, and be sure container is compatible with the intermediate

Use rated storage cabinets or safety cans whenever possible—required for >10 gal. of flammables.

Cold rooms, refrigerators, and freezers have additional requirements, particularly for flammables.

Ordering Process

Inquiry

Quotation

Communication

Order confirming

Deposit payment

Production

Testing and debugging

Balance payment

Packing

Delivery

Customer receiving

After service

Packaging and Shipping

Packaging	Vacuum-sealed vials (1 mg, 5 mg, 10 mg, 100 mg, 1 g) or bulk quantities
Shipping	We commonly use international express services such as DHL, FedEx, and UPS.

FAQ

Q: What are the characteristics of intermediates?

A: Intermediates are typically very short-lived and are often highly reactive. They are usually not observed in the final reaction mixture but can sometimes be detected using special instrumental techniques or inferred from the reaction products and reactants.

Q: How do you know which intermediate is most stable?

A: Step 1: Identify the types of carbocations.
Step 2: Analyze the given structures.
Step 3: Determine the stability based on alkyl groups.
Step 4: Evaluate the inductive effect.
Step 5: Compare the stability.

Q: How to tell the difference between a catalyst and an intermediate?

A: In a chemical reaction, a catalyst speeds up a reaction without being consumed, while an intermediate is formed and consumed during the reaction.

Q: How do Pharmaceutical Intermediates differ from APIs?

A: Pharmaceutical intermediates are intermediate products in the synthesis process of APIs, while APIs are the active ingredients in drugs that exert therapeutic effects.

Q: How do you identify intermediate?

A: It was produced in the first elementary step, then reacts in the second elementary step. An intermediate is a species which appears in the mechanism of a reaction, but not in the overall balanced equation. An intermediate is always formed in an early step in the mechanism and consumed in a later step.

Q: What is the stability of an intermediate?

A: The intermediate is stable only during the reaction, and can not exist outside of the reaction. More than one intermediate can be formed then used over the course of a reaction. The intermediate is less stable, thus existing at a lower energy than the activated complex.

As one of the most professional intermediate manufacturers and suppliers in China, we also support customized service. Please feel free to buy bulk high quality intermediate in stock here from our factory. For price consultation, contact us.

Intermediate