Your Professional Chemical Intermediate Supplier
 

TNJONE is a professional manufacturer of pharmaceutical raw materials, APIs, peptides, and intermediates with over 10 years of industry experience. We operate a GMP-compliant factory in Shaanxi, China, serving pharmaceutical, research, and healthcare applications.

Strict Quality Control

Professional QA and QC teams ensure stable purity, reliable performance, and full production traceability.

Custom Manufacturing

Advanced production and testing equipment support flexible OEM/ODM solutions for different product requirements.

Reliable Supply & Delivery

Efficient production management and professional logistics help ensure stable supply and safe global transportation.

 
 

Specification

 

Chemical name

4,4'-(Hexafluoroisopropylidene)diphthalic anhydride

Common abbreviation

6FDA

Molecular formula

C₁₉H₆F₆O₆

Molecular weight

~444.24 g/mol

CAS number

1107-00-2

Appearance

White crystalline powder

Odor

Odorless

Melting point

~238–242 °C

Solubility

Soluble in polar aprotic solvents (e.g., DMF, DMAc, NMP, DMSO)

Insoluble or poorly soluble in water and nonpolar solvents

Stability

Stable under dry, inert conditions; sensitive to moisture due to anhydride functionality

 

Advantages of Chemical Intermediate
 
 
 

Building Blocks for APIs

Active pharmaceutical ingredients (APIs) are the core components responsible for the therapeutic effects of drugs. However, APIs cannot be produced directly. Instead, they are synthesized through a series of chemical reactions that require specific intermediates to build the molecular framework of the final drug.

 
 

Customizable Synthesis Routes

The pharmaceutical industry often requires tailored synthesis routes to create specific molecular structures for new medications. Chemical intermediates provide flexibility in the synthesis process, allowing pharmaceutical manufacturers to fine-tune reactions and optimize pathways to produce high-purity APIs.

 
 

Ensuring Drug Purity and Efficacy

The quality of chemical intermediates has a direct impact on the purity and efficacy of the final pharmaceutical product. Impurities in intermediates can lead to unwanted side effects, reduced potency, or even drug recalls, which can be costly and damaging to a company’s reputation.

 
 

Cost-Effective Production

In addition to their importance in drug efficacy and safety, chemical intermediates also play a significant role in controlling manufacturing costs. Pharmaceutical production is expensive due to the complexity of chemical reactions, the need for high-purity materials, and compliance with stringent regulatory standards.

 

 

Applications of Chemical Intermediate
 
productcate-650-500

Antibiotics
Many antibiotics, including penicillins and cephalosporins, are produced using specific chemical intermediates that are crucial for constructing the beta-lactam ring, the core structure of these drugs.

 

Anticancer Drugs
Chemotherapy medications require the careful assembly of complex molecular structures. Intermediates allow for the precision needed to synthesize cytotoxic agents that target cancer cells effectively.

 

Cardiovascular Drugs
Drugs that regulate blood pressure, cholesterol, or heart function often rely on intermediates to ensure precise therapeutic properties and to maintain high levels of efficacy.

 

Antiviral and Antiretroviral Drugs
Intermediates are essential in the synthesis of drugs that target viral infections such as HIV, Hepatitis, or influenza, helping to develop effective treatments for viral diseases.

 

 
Synthesis Methods for Chemical Intermediate

Addition reactions

Reactions where two or more substances chemically react to form a compound with a higher molecular weight. For example, the reaction between ethylene and hydrogen to produce acetylene involves an addition reaction.

Elimination reactions

Reactions where a compound decomposes into two or more smaller compounds. For example, the reaction between acetylene and hydrogen to produce ethanol involves an elimination reaction.

Substitution reactions

Reactions where an atom or group is replaced by another atom or group. For example, the reaction between hydrochloric acid and ethanol to produce vinyl chloride involves a substitution reaction where a chlorine atom replaces a hydrogen atom in ethanol.

Rearrangement reactions

Reactions where atoms or groups within a molecule undergo positional changes. For example, aromatic ring rearrangements can occur in benzene, leading to the formation of new compounds.

 

Precautions for the Storage of Chemical Intermediates

 

4-Biphenylylmethyl Acrylate Powder CAS 54140-58-8

Temperature:

Store in a cool, dry, and adequately ventilated area away from direct sunlight and heat sources.

5,5'-oxybis(isobenzofuran-1,3-dione) Powder CAS 1823-59-2

Ventilation:

Use designated, ventilated storage cabinets to manage volatile, toxic, or malodorous chemical vapors.

4,4'-(Hexafluoroisopropylidene)diphthalic Anhydride Powder CAS 1107-00-2

Closed & Sealed:

Keep all containers tightly closed to prevent evaporation, vapor accumulation, and leakage if tipped.

 

Ordering Process

 

Inquiry

1

>>

Quotation

2

>>

Communication

3

>>

Order confirming

4

>>

Deposit payment

5

>>

Production

6

Testing and debugging

7

>>

Balance payment

8

>>

Packing 

9

>>

Delivery

10

>>

Customer receiving

11

>>

After service

12

 

Packaging and Shipping

 

Packaging

Vacuum-sealed vials (1 mg, 5 mg, 10 mg, 100 mg, 1 g) or bulk quantities

Shipping

We commonly use international express services such as DHL, FedEx, and UPS.

 

FAQ

 

Q: What are the different types of chemical intermediates?

A: To reaction pathways in chemistry, it is essential to comprehend the types of intermediates. Carbonications, carbanions, radicals, carbenes, and nitrenes are common chemical intermediates. Carbocations are positively charged, while carbanions are negatively charged. Radicals, are fundamental to organic reactions.

Q: What forms of chemical intermediate are available?

A: Chemical intermediate is available in powder, liquid, crystal, and granule forms. Different chemical intermediate forms are chosen depending on production requirements and transportation needs. Proper packaging and storage help maintain product quality and chemical stability during use.

Q: Why is purity important for chemical intermediate?

A: High purity is important because chemical intermediate directly affects the performance and quality of the final product. Impure chemical intermediate may cause unstable reactions or lower production efficiency. Manufacturers use strict testing methods to ensure product consistency and safety.

Q: What are common raw materials for chemical intermediate?

A: Chemical intermediate can be made from organic compounds, petrochemical materials, natural extracts, or industrial chemicals. Different raw materials are selected according to the final application. High-quality raw materials help improve chemical intermediate performance and production stability.

As one of the most professional chemical intermediate manufacturers and suppliers in China, we also support customized service. Please feel free to buy bulk high quality chemical intermediate in stock here from our factory. For price consultation, contact us.

ODPA Powder, 4 Biphenylylmethyl Acrylate Powder CAS 54140 58 8, 3218-36-8
Send Inquiry