Introduction to Coenzyme Q10 (CoQ10) Powder
Coenzyme Q10 (CoQ10) Powder (Ubiquinone,CAS: 303-98-0), is a lipid-soluble quinone compound naturally present in the mitochondria of all eukaryotic cells . As a critical coenzyme in cellular energy metabolism and a potent antioxidant, it plays dual foundational roles: facilitating the synthesis of ATP (adenosine triphosphate)-the primary energy currency of cells-and neutralizing free radicals to protect cell membranes from oxidative damage.
Human bodies endogenously produce Coenzyme Q10 (CoQ10) Powder, but production declines with age (by 50% after 60 years) and is further reduced by factors like statin use, stress, and chronic diseases . With a molecular weight of 863.36, the compound's structure-featuring a benzoquinone core and a 10-isoprenoid side chain-enables its unique biological functions, making it an indispensable raw material in nutraceuticals, pharmaceuticals, cosmetics, and functional foods.
Our Coenzyme Q10 (CoQ10) Powder is produced via advanced microbial fermentation technology, ensuring exceptional purity (≥98%), bioactivity, and consistency to meet the stringent standards of global professional buyers.
Technical Specifications of Coenzyme Q10 (CoQ10) Powder
|
Item |
Specification |
Test Method |
|
Product Name |
Coenzyme Q10 (CoQ10) Powder (Ubiquinol) |
- |
|
CAS Number |
303-98-0 |
HPLC Confirmation |
|
Molecular Formula |
C59H90O4 |
Elemental Analysis |
|
Molecular Weight |
865.38 |
Mass Spectrometry |
|
Appearance |
Pale yellow to off-white crystalline powder |
Visual Inspection (ISO 6353-1) |
|
Purity |
97.0–100.0% |
HPLC |
|
Melting Point |
58–62 °C |
Differential Scanning Calorimetry (DSC) |
|
Loss on Drying |
≤5.0% |
ISO 787-2 (105°C, 2hrs) |
|
Ash Content |
≤1.0% |
ISO 787-11 |
|
Heavy Metal Limits |
Lead (Pb): ≤0.5ppm (As): ≤1.0ppm (Hg): ≤0.1ppm (Cd): ≤0.1ppm |
ICP-MS (ISO 11212-6) |
|
Residual Solvents |
Ethanol: ≤5000ppm Heptane: ≤5000ppm |
Gas Chromatography (GC) |
|
Microbial Limits |
Total Plate Count: ≤1000 CFU/gYeast & Mold: ≤100 CFU/gs: ≤10 CFU/g (E. coli, Salmonella): Negative |
USP 1>, ISO 6579 |
|
Solubility |
Partially water-soluble (5mg/mL); Soluble in ethanol, glycerol |
Solubility Test (USP |
|
Storage Stability |
24 months at -20°C (sealed, protected from light/heat); 6 months at 25°C (desiccated) |
Accelerated Stability Testing (ICH Q1A) |
|
Packaging |
Aluminum foil bags (1kg/5kg/25kg) or fiber drums (25kg) with vacuum-sealed nitrogen flushing |
- |
Key Applications of Coenzyme Q10 (CoQ10) Powder
1. Nutraceuticals & Dietary Supplements
Coenzyme Q10 (CoQ10) Powder is a globally recognized functional ingredient with clinically validated benefits:
•Cardiovascular Health: Enhances ATP production in cardiac mitochondria, improving heart function, reducing blood pressure, and alleviating symptoms of heart failure (60-70% efficacy in clinical trials) . It also mitigates statin-induced CoQ10 deficiency, a common side effect of cholesterol-lowering drugs.
•Energy Enhancement: Boosts mitochondrial function in skeletal muscles, reducing fatigue and improving exercise performance-ideal for sports nutrition supplements.
•Anti-Aging & Neuroprotection: Neutralizes free radicals, slowing cellular aging; supports brain health by protecting neurons from oxidative stress, potentially reducing the risk of Parkinson's and Alzheimer's diseases.
2. Pharmaceuticals & Clinical Research
•Active Pharmaceutical Ingredient (API): Coenzyme Q10 (CoQ10) Powder is used in formulations for treating heart failure, hypertension, and mitochondrial disorders. The reduced form (ubiquinol) is preferred for injectable drugs due to its higher solubility and bioavailability .
•Reference Standard: Serves as a calibration standard in HPLC-based drug quality control, complying with USP, EP, and Chinese Pharmacopoeia requirements .
3. Cosmetics & Personal Care
Coenzyme Q10 (CoQ10) Powder is a premium anti-aging ingredient in skincare:
•Anti-Wrinkle & Rejuvenation: Stimulates collagen synthesis, reduces fine lines and wrinkles by 30-40% (8-week clinical study).
•Oxidative Protection: Neutralizes UV-induced free radicals, preventing photoaging and hyperpigmentation.
•Moisturization: Enhances skin barrier function by improving lipid metabolism in keratinocytes.
4. Functional Foods & Beverages
•Added to energy drinks, protein bars, and fortified foods (e.g., yogurt, cereals) to enhance energy metabolism and antioxidant capacity.
•Used as a natural food additive (E number pending) for its yellow-orange pigment properties, replacing synthetic dyes in confectionery and beverages.
5. Veterinary Medicine
•Formulated into pet supplements to support cardiac health in senior dogs and cats, improve energy levels, and alleviate age-related cognitive decline.
Quality Assurance of Coenzyme Q10 (CoQ10) Powder
We maintain a strict quality management system to ensure Coenzyme Q10 (CoQ10) Powder meets global standards:
•Comprehensive Testing: Each batch undergoes 200+ quality tests, including purity (HPLC), heavy metal screening (ICP-MS), residual solvent analysis (GC), microbial detection, and stability testing. A full Certificate of Analysis (COA) is provided with every order.
•Traceability System: From fermentation substrate sourcing to finished product, each batch is assigned a unique traceability code, enabling full transparency of the production chain.
•Customization Services: We offer tailored solutions, including particle size adjustment (100-500 mesh), water-soluble formulations (via cyclodextrin complexation), and sterile packaging for pharmaceutical applications.
Why Choose Our Coenzyme Q10 (CoQ10) Powder?
For professional buyers, our Coenzyme Q10 (CoQ10) Powder offers unparalleled value:
•Superior Purity & Bioactivity: Fermentation-derived product with ≥98% purity (HPLC-verified), matching natural human CoQ10 structure for optimal absorption.
•Dual-Form Availability: Oxidized (cost-effective for supplements) and reduced (high-bioavailability for pharmaceuticals/cosmetics) forms to meet diverse application needs.
•Reliable Supply Chain: Scalable production capacity (200+ tons/year) and strategic inventory ensure on-time delivery for bulk orders, even during supply chain disruptions.
•Technical Expertise: Dedicated R&D team provides formulation support, stability data, and regulatory documentation (e.g., MSDS, Certificate of Origin) to accelerate product development.
Whether you require Coenzyme Q10 (CoQ10) Powder for nutraceuticals, pharmaceuticals, cosmetics, or functional foods, our product delivers consistent quality, performance, and compliance-backed by decades of expertise in microbial fermentation and natural bioactive ingredients.
Hot Tags: coenzyme q10 (coq10) powder cas 303-98-0, China coenzyme q10 (coq10) powder cas 303-98-0 manufacturers, suppliers, factory, 303-98-0, Garcinia Cambogia Extract Powder, Ginkgo Biloba Extract Powder, NADH Powder, NADH Powder CAS 606 68 8, pure nad powder
