Product Introduction
L-Ergothioneine Powder is a naturally occurring sulfur-containing amino acid derivative with exceptional antioxidant stability. Chemically identified as (2-mercaptohistidine trimethylbetaine), L-Ergothioneine is widely recognized for its unique molecular structure, which enables strong resistance to oxidation and long-term stability compared to many conventional antioxidants.
Our Manufacture 99% Ergothioneine Powder (CAS: 497-30-3) is produced under strict quality control systems, ensuring high purity, consistent particle size, and excellent batch-to-batch reproducibility. This makes it suitable for nutraceutical formulations, cosmetic applications, functional foods, and laboratory research.In addition to the fermented type, we also provide L-ergothioneine derived from Agaricus blazei extract, available in purities of 0.5% and 1%.
Unlike common antioxidants that degrade rapidly under heat or light, L-Ergothioneine Powder demonstrates outstanding thermal and chemical stability. This property has driven increasing global demand, especially in dietary supplements, anti-aging skincare formulations, and advanced health-focused products.

Certificate of Analysis

Functions and Applications
The multifaceted functionality of 99% Ergothioneine Powder makes it a cornerstone ingredient across multiple high-growth industries.
A. Nutraceuticals & Dietary Supplements:
Cellular Energy & Mitochondrial Support: EGT accumulates within mitochondria, helping to maintain optimal function and protect these cellular powerhouses from oxidative damage associated with energy production.
Systemic Antioxidant Defense: As a potent, stable, and cell-permeable antioxidant, it supports the body's natural defenses against free radicals, contributing to overall wellness and vitality.
Inflammatory Response Management: By modulating key signaling pathways, it helps support a healthy, balanced inflammatory response in the body.
Liver Health Support: Its selective accumulation in the liver aids in protecting hepatic cells from various stressors.
B. Cosmestic & Skincare:
Ultimate Skin Antioxidant: Protects skin cells from environmental aggressors like UV radiation and pollution, preventing premature aging and photo-damage.
Anti-Aging & Wrinkle Reduction: Helps reduce the appearance of fine lines and wrinkles by protecting collagen and elastin from degradation.
Skin Brightening & Tone Enhancement: Inhibits tyrosinase activity and melanin production, helping to manage hyperpigmentation and promote a more even, radiant skin tone.
Anti-Inflammatory & Soothing: Calms irritated skin, reducing redness and sensitivity, ideal for post-procedure care or sensitive skin formulations.
Enhanced Product Stability: Acts as a stabilizer in formulations, protecting other active ingredients (e.g., vitamins, peptides) from oxidation, thereby extending product shelf-life.
C. Functional Foods & Beverages:
Stable Fortification: Due to its exceptional heat and pH stability, L-Ergothioneine Powder is ideal for fortifying a wide range of products-from energy bars and sports nutrition powders to ready-to-drink beverages and dairy alternatives-without losing efficacy.
Formula Suggestions
A. Advanced Anti-Aging Serum
L-Ergothioneine (99% Powder): 0.5% - 1.0%
Vitamin C (Ethyl Ascorbic Acid): 2%
Niacinamide: 5%
Hyaluronic Acid: 1%
Base: Appropriate water-based serum gel.
Key Benefit: Multi-pathway defense and rejuvenation.
B. High-Performance Cognitive Support Capsule
L-Ergothioneine (99% Powder): 5mg - 30mg per serving
Phosphatidylserine: 100mg
Citicoline: 250mg
Bacopa Monnieri Extract: 300mg
Key Benefit: Comprehensive neuronal protection and cognitive fuel.
C. Endurance & Recovery Sports Powder
L-Ergothioneine (99% Powder): 10mg - 50mg per serving
Branched-Chain Amino Acids (BCAAs): 5g
Creatine Monohydrate: 3g
Electrolyte Blend
Key Benefit: Supports mitochondrial efficiency and reduces exercise-induced oxidative stress.
Frequently Asked Questions (FAQ)
Q: What is the primary difference between L-Ergothioneine and other antioxidants like glutathione?
A: While both are crucial, L-Ergothioneine has a dedicated cellular transporter (OCTN1), ensuring efficient uptake even at low doses. It is also remarkably stable and does not auto-oxidize easily, making it a more persistent and reliable antioxidant within complex biological systems and finished product formulations.
Q: Is L-Ergothioneine safe for long-term consumption?
A: Yes. L-Ergothioneine Powder is a natural, food-grade compound found in the human diet (e.g., in mushrooms, black beans). It is Generally Recognized As Safe (GRAS) for use in foods and beverages .
Q: What is the recommended dosage in final formulations?
A: Dosage varies by application. In dietary supplements, common daily doses range from 5mg to 30mg. In topical skincare, effective concentrations range from 0.1% to 1.0%.
Q: How should this powder be stored and handled?
A: For long-term stability (24 months), store unopened containers at 2-8°C in a dry environment. For daily use in a manufacturing setting, keep the material in a cool, dry place away from direct light and moisture. Standard hygiene and powder-handling procedures apply.
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